David's Sling

Obscurins: Goliaths and Davids Take over Non-Muscle Tissues

Obscurins comprise a family of proteins originally identified in striated muscles, where they play essential roles in myofibrillogenesis, cytoskeletal organization, and Ca(2+) homeostasis. They are encoded by the single OBSCN gene, and are composed of tandem adhesion domains and signaling motifs. To date, two giant obscurin isoforms have been described in detail that differ only at the extreme ...

Correction: Obscurins: Goliaths and Davids Take over Non-Muscle Tissues

[This corrects the article DOI: 10.1371/journal.pone.0088162.].

Early results of pubovaginal sling lysis by midline sling incision.

OBJECTIVES To describe a simplified technique and results of pubovaginal sling lysis by incision of the sling in the midline by way of a transvaginal approach. METHODS We reviewed the charts of 19 women who underwent pubovaginal sling lysis for obstruction. Patients presenting with retention, incomplete emptying or storage, or voiding symptoms suggesting obstruction after pubovaginal sling pl...

Polyethylene sling for procidentia.

Pulmonary artery sling.

Pulmonary artery sling is a rare cause of respiratory distress the embryological origin of which is not known. Two patients with this abnormality, both of whom are now thriving, are described. Surgery was necessary at the age of 5 1/2 years in one child, who also had an atrial septal defect. The other child, at the age of 2 years, shows improvement of her wheezing, cough, and breathlessness des...